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1

1,3,5-Trisubstituted Pyrazoles as Potent Negative Allosteric Modulators of the mGlu 2/3 Receptors

Van Gool, Michiel, Alonso De Diego, Sergio A., Delgado, Oscar, Trabanco, Andrés A., Jourdan, Fabrice, Macdonald, Gregor J., Somers, Marijke, Ver Donck, Luc

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 2.17 MB

english, 2017

2

A Bayesian K-PD model for synergy: A case study

La Gamba, Fabiola, Jacobs, Tom, Geys, Helena, Ver Donck, Luc, Faes, Christel

Journal:

Pharmaceutical Statistics

Année:

2018

Langue:

english

Fichier:

PDF, 1006 KB

english, 2018

3

Strengths and limitations of highâthroughput sequencing for the diagnosis of inherited bleeding and platelet disorders

Ver Donck, Fabienne, Downes, Kate, Freson, Kathleen

Journal:

Journal of Thrombosis and Haemostasis

Année:

2020

Fichier:

PDF, 27.81 MB

2020

4

Cytomics and drug discovery

Peter Van Osta, Kris Ver Donck, Luc Bols, Johan Geysen

Journal:

Cytometry Part A

Année:

2006

Langue:

english

Fichier:

PDF, 47 KB

english, 2006

5

339 Case report: Ziconotide treatment for a neuropathic and a degenerative pain problem

Journal:

European Journal of Pain

Année:

2007

Langue:

english

Fichier:

PDF, 54 KB

english, 2007

6

Population analysis of the non linear red blood cell partitioning and the concentration-effect relationship of draflazine following various infusion rates

E. Snoeck, V. Piotrovskij, P. Jacqmin, A. Van Peer, M. Danhof, K. Ver Donck, R. Woestenborghs, H. Van Belle, L. Van Bortel, R. Van Gool, A. G. Dupont, J. Heykants

Journal:

British Journal of Clinical Pharmacology

Année:

1997

Langue:

english

Fichier:

PDF, 945 KB

english, 1997

7

Purine metabolism in the heart

Journal:

International Journal of Clinical Pharmacy

Année:

1994

Langue:

english

Fichier:

PDF, 72 KB

english, 1994

8

Purine metabolism in the heart

Journal:

International Journal of Clinical Pharmacy

Année:

1994

Langue:

english

Fichier:

PDF, 1.20 MB

english, 1994

9

Effects of lidoflazine and mioflazine against potassium and veratrine induced shape changes in isolated rat cardiac myocytes

L. Ver Donck, Guo-Shu Liu, G. Vandeplassche, M. Borgers

Journal:

Basic Research in Cardiology

Année:

1987

Langue:

english

Fichier:

PDF, 1.60 MB

english, 1987

10

Key lectures

J. Balzarini, M. Gross, T. Kulikowski, G. J. Peters, J. G. Puig, H. A. Simmonds, K. Ver Donck, T. W. Stone, G. Weber

Journal:

International Journal of Clinical Pharmacy

Année:

1993

Langue:

english

Fichier:

PDF, 277 KB

english, 1993

11

Mapping slow waves and spikes in chronically instrumented conscious dogs: implantation techniques and recordings

L. Ver Donck, W. J. E. P. Lammers, B. Moreaux, D. Smets, J. Voeten, J. Vekemans, J. A. J. Schuurkes, B. Coulie

Journal:

Medical and Biological Engineering and Computing

Année:

2006

Langue:

english

Fichier:

PDF, 762 KB

english, 2006

12

Mapping slow waves and spikes in chronically instrumented conscious dogs: automated on-line electrogram analysis

Wim J. E. P. Lammers, B. Michiels, J. Voeten, L. Ver Donck, J. A. J. Schuurkes

Journal:

Medical and Biological Engineering and Computing

Année:

2008

Langue:

english

Fichier:

PDF, 488 KB

english, 2008

13

The implications of non-linear red blood cell partitioning for the pharmacokinetics and pharmacodynamics of the nucleoside transport inhibitor draflazine

E. SNOECK, P. JACQMIN, A. VAN PEER, M. DANHOF, K. VER DONCK, H. VAN BELLE, R. WOESTENBORGHS, R. CRABBÉ, R. VAN GOOL, A. DUPONT, J. HEYKANTS

Journal:

British Journal of Clinical Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 833 KB

english, 1996

14

Spatial determination of successive spikes in the isolated cat duodenum

W. J. E. P. Lammers, C. Faes, B. Stephen, L. Bijnens, L. Ver Donck, J. A. J. Schuurkes

Journal:

Neurogastroenterology & Motility

Année:

2004

Langue:

english

Fichier:

PDF, 552 KB

english, 2004

15

Electrical activity in the rectum of anaesthetized dogs

W. J. E. P. Lammers, F. A. Abazer, L. Ver Donck, D. Smets, J. A. J. Schuurkes, B. Coulie

Journal:

Neurogastroenterology & Motility

Année:

2006

Langue:

english

Fichier:

PDF, 820 KB

english, 2006

16

Robust anti-arrhythmic efficacy of verapamil and flunarizine against dofetilide-induced TdP arrhythmias is based upon a shared and a different mode of action

A Oros, MJ Houtman, P Neco, AM Gomez, S Rajamani, P Oosterhoff, NJ Attevelt, JD Beekman, MAG Van Der Heyden, L Ver Donck, L Belardinelli, S Richard, G Antoons, MA Vos, for the CONTICA investigators

Journal:

British Journal of Pharmacology

Année:

2010

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2010

17

A Prospective, Open-label Study of Long-term Intrathecal Ziconotide for Chronic Nonmalignant Back Pain: A Case Report

Ann Ver Donck, Sanjeeva Dissanayake, An Bostyn, Piet Vercruysse

Journal:

Neuromodulation: Technology at the Neural Interface

Année:

2006

Langue:

english

Fichier:

PDF, 125 KB

english, 2006

18

An Open-Label, Multicenter Study of the Safety and Efficacy of Intrathecal Ziconotide for Severe Chronic Pain When Delivered via an External Pump

Ann Ver Donck, Ronald Collins, Richard L. Rauck, Petre Nitescu

Journal:

Neuromodulation: Technology at the Neural Interface

Année:

2008

Langue:

english

Fichier:

PDF, 129 KB

english, 2008

19

Calcium-Sensitizing Drugs: Positive Inotropy by Enhanced Sensitivity of the Contractile Apparatus to Calcium

Journal:

Cardiovascular Therapeutics

Année:

1996

Langue:

english

Fichier:

PDF, 1.84 MB

english, 1996

20

Intrathecal Therapy: What Has Changed With the Introduction of Ziconotide

Hans G. Kress, Karen H. Simpson, Paolo Marchettini, Ann Ver Donck, Giustino Varrassi

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 245 KB

english, 2009

21

Effect of peripheral obestatin on food intake and gastric emptying in ghrelin-knockout mice

I Depoortere, T Thijs, D Moechars, B De Smet, L Ver Donck, T L Peeters

Journal:

British Journal of Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 163 KB

english, 2008

22

Endogenous and exogenous ghrelin enhance the colonic and gastric manifestations of dextran sodium sulphate-induced colitis in mice

B. De Smet, T. Thijs, D. Moechars, B. Colsoul, L. Polders, L. Ver Donck, B. Coulie, T. L. Peeters, I. Depoortere

Journal:

Neurogastroenterology & Motility

Année:

2009

Langue:

english

Fichier:

PDF, 433 KB

english, 2009

23

Determination of the source of increased serotonin (5-HT) concentrations in blood and peritoneal fluid of colic horses with compromised bowel

C. DELESALLE, G. R. van de WALLE, C. NOLTEN, L. ver DONCK, A. van HEMELRIJCK, W. DRINKENBURG, H. DE BOSSCHERE, P. CLAES, P. DEPREZ, L. LEFERE, S. TORFS, R. A. LEFEBVRE

Journal:

Equine Veterinary Journal

Année:

2008

Langue:

english

Fichier:

PDF, 291 KB

english, 2008

24

Obestatin Induction of Early-Response Gene Expression in Gastrointestinal and Adipose Tissues and the Mediatory Role of G Protein-Coupled Receptor, GPR39

Zhang, J. V., Jahr, H., Luo, C.-W., Klein, C., Van Kolen, K., Ver Donck, L., De, A., Baart, E., Li, J., Moechars, D.

Journal:

Molecular Endocrinology

Année:

2008

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2008

25

Pharmacological studies of arrhythmias induced by rose bengal photoactivation

Michèle Bernier, Yoshiki Kusama, Marcel Borgers, Luc Ver Donck, Oscar Valdes-Aguilera, Douglas C. Neckers, David J. Hearse

Journal:

Free Radical Biology and Medicine

Année:

1991

Langue:

english

Fichier:

PDF, 849 KB

english, 1991

26

The effects of cholinergic stimulation and of nucleoside transport inhibition on spikes and spike patches in the canine small intestine in vivo

Wim J.E.P. Lammers, L. Ver Donck, Jan A.J. Schuurkes, Dirk Smets, Betty Stephen

Journal:

European Journal of Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 2.18 MB

english, 2007

27

Changes in Ultrastructural Calcium Distribution in Goat Atria During Atrial Fibrillation

Jannie Ausma, Gerrit D Dispersyn, Hans Duimel, Fred Thoné, Luc Ver Donck, Maurits A Allessie, Marcel Borgers

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2000

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2000

28

Preferential block of the veratridine-induced, non-inactivating Na+ current by R56865 in single cardiac Purkinje cells

Fons Verdonck, Frieda V. Bielen, Luc Ver Donck

Journal:

European Journal of Pharmacology

Année:

1991

Langue:

english

Fichier:

PDF, 970 KB

english, 1991

29

Ca2+-overload and cell death is mediated by pathological modification of ion channels

L. Ver Donck, M. Borgers

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1990

Langue:

english

Fichier:

PDF, 99 KB

english, 1990

30

R 56 865, a new cardioprotective principle based on prevention of ion channel pathology

M. Borgers, L. Ver Donck

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1990

Langue:

english

Fichier:

PDF, 94 KB

english, 1990

31

Prevention of Na+-channel dysfunction in pathological conditions: a new cardioprotective principle for R 56865

Luc Ver Donck, Marcel Borgers

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1990

Langue:

english

Fichier:

PDF, 102 KB

english, 1990

32

Protection against lysophosphatidylcholne induced Ca2+-overload in rabbit cardiomyocytes

Luc Ver Donck, Greet Verellen, Fons Verdonck, Marcel Borgers

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1990

Langue:

english

Fichier:

PDF, 101 KB

english, 1990

33

Nucleoside transport inhibition and fMLP-stimulated whole blood luminescence

Kris L.A. Ver Donck, Willy J.L. Verheyen, Herman Van Belle

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1991

Langue:

english

Fichier:

PDF, 201 KB

english, 1991

34

Effect of phosphodiesterase-inhibitors on low pH- and Ca2+-induced impaired contractile response of paced intact isolated cardiomyocytes

Luc Ver Donck, Greet Verellen, Hugo Geerts, Didier de Chaffoy, Marcel Borgers

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1991

Langue:

english

Fichier:

PDF, 101 KB

english, 1991

35

Effect of high K+ on intracellular Ca2+ in isolated rat cardiomyocytes

Luc Ver Donck, Greet Verellen, Roger Nuyens, Hugo Geerts, Marcel Borgers, Fons Verdonck

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1991

Langue:

english

Fichier:

PDF, 97 KB

english, 1991

36

Quantification of arrhythmogenicity in spontaneously beating cultures of neonatal rat cardiomyocytes

Hugo Geerts, Luc Ver Donck, Greet Verellen

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1991

Langue:

english

Fichier:

PDF, 98 KB

english, 1991

37

Cardioprotective drugs antagonize high Ca2+-induced arrhythmias in cultures of spontaneously beating neonatal rat cardiomyocytes

Luc Ver Donck, Greet Verellen, Carine Vanherck, Hugo Geerts, Marcel Borgers

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1991

Langue:

english

Fichier:

PDF, 93 KB

english, 1991

38

Attenuation of catecholamine cardiotoxicity by R75231, a specific nucleoside transport inhibitor

Kris L.A. Ver Donck, Willy J.L. Verheyen, Herman Van Belle

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1991

Langue:

english

Fichier:

PDF, 112 KB

english, 1991

39

R 56865 preserves myocardial Na+ and Ca2+ homeostasis

Marcel Borgers, Luc Ver Donck, Godelieve Vandeplassche

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 104 KB

english, 1992

40

R 56865: a new cytoprotective principle by inhibition of Na+- and Ca2+-overload

Luc Ver Donck, Marcel Borgers, Fons Verdonck

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 91 KB

english, 1992

41

Altered contractile behaviour of cardiomyocytes from cardiomyopathic hamsters

L. Ver Donck, G. Verellen, H. Geerts, M. Borgers

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 101 KB

english, 1992

42

Nebivolol enhances survival of cardiomyopathic hamsters with congestive heart failure

L. Ver Donck, L. Wouters, H.-G Olbrich, E. Mutschler, M. Borgers

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 98 KB

english, 1992

43

Effect of R 56865 on oscillatory-type Ca2+ release in rat cardiomyocytes

Luc Ver Donck, Greet Verellen, Hugo Geerts, Marcel Borgers

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 109 KB

english, 1992

44

Antiaggregation in human blood by nucleoside transport inhibition. Comparison with known antithrombotics

Kris Ver Donck, Willy Verheyen, Annemie Heylen, Herman Van Belle

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 96 KB

english, 1992

45

Lysophosphatidylcholine-induced Ca2+-overload in isolated cardiomyocytes and effect of cytoprotective drugs

Luc Ver Donck, Greet Verellen, Hugo Geerts, Marcel Borgers

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 4.87 MB

english, 1992

46

A novel library screen identifies immunosuppressors that promote osteoblast differentiation

Ariana Darcy, Micah Meltzer, Joseph Miller, Steven Lee, Scott Chappell, Kris Ver Donck, Monty Montano

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.87 MB

english, 2012

47

Isolated rat cardiac myocytes as an experimental model to study calcium overload: The effect of calcium-entry blockers

Luc Ver Donck, Petrus J. Pauwels, Godelieve Vandeplassche, Marcel Borgers

Journal:

Année:

1986

Langue:

english

Fichier:

PDF, 513 KB

english, 1986

48

P.1.c.015 Differential effects of acute and sub-chronic PCP in rodent cognition: reversal with a selective mGlu2 negative allosteric modulator RO4491533

S. Embrechts, H. Lavreysen, L. Ver Donck, D.J. Pemberton

Journal:

European Neuropsychopharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 63 KB

english, 2012

49

P.2.f.003 Acute and repeated ketamine treatment leads to biphasic effects in the DRL72 test, a model for depression in rats

P. De Haes, M. Meynen, L. Ver Donck, A. Bouwknecht

Journal:

European Neuropsychopharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 73 KB

english, 2012

50

Isolated rat cardiomyocytes as an experimental model for studying acute cardiotoxicity of cyclosporin A

Hans G. Olbrich, S. Dols, L. Ver Donck, G. Kober, M. Kaltenbach, E. Mutschler

Journal:

International Journal of Cardiology

Année:

1990

Langue:

english

Fichier:

PDF, 725 KB

english, 1990